Drug Hunter - Computational Chemist

About Aqemia

Aqemia is an in silico drug discovery start-up, whose ambition is to discover rapidly more innovative therapeutic molecules with better chances of success. How? Just like an AI can learn to play chess, Aqemia’s generative AI learns to invent relevant compounds thanks to unique Statistical Mechanics algorithms predicting drug-target affinity among other properties. Aqemia’s differentiation lies in its affinity prediction both accurate and 10 000x faster than competition, enabling efficient guidance of generation towards compounds with better chances to become drugs.

Aqemia is a spin-off of the École Normale Supérieure Paris leveraging disruptive algorithms from 8 years of research. Aqemia’s team is composed of a dozen of high profiles at the crossroads of Medicinal Chemistry, Statistical Mechanics and Artificial Intelligence.

Founded in June 2019, we have raised €1.6M with leading VC fund Elaia Partners, Bpifrance.

We’re looking for a 

Drug Hunter - Computational Chemist

to join our core team and make an impact on a critical challenge: discovering drug candidates to cure key diseases. You will work in an interdisciplinary team of drug hunters, physicists, chemists and ML engineers

If this sounds exciting to you, come and join us!

Job description​

We’re looking for a computational Chemist alias Drug Hunter to join our core team and make an impact on a critical challenge: discovering drug candidates to cure key diseases. You will work in an interdisciplinary team of medicinal chemists, physicists and ML engineers.

As a Drug Hunter you will leverage our drug discovery pipeline and interact with the team to develop project-specific approaches that yield new drug candidates.

Your responsibilities

  • Develop structural biology knowledge and bibliography about specific projects/targets
  • Screen molecules using our drug-target affinity computation pipeline and other chemo-info softwares
  • Propose and discuss relevant molecules with Aqemia drug hunting team and clients
  • Collaborate closely with AI team and bring your drug hunter perspective and insights

Preferred experience

Your profile:

  • You have a Ph.D or a Master in Cheminformatics, Bioinformatics, Computational Biology, Computational Chemistry or a related discipline
  • You have 2-4+ years hands-on experience in computational chemistry applied to drug discovery including docking, screening, QSAR, structure- or ligand-based modelling and associated softwares/programming
  • You need to understand the fundamentals of bio-molecular interactions and molecular design
  • You have strong coding skills in at least one programming language (Python, Fortran, others)
  • Knowledge structural biology and/or Medicinal chemistry background is a plus

You should join us if…

  • You are passionate about solving difficult problems on topics that really matter
  • You are curious, willingful and dynamic
  • You want to grow and help others grow as well
  • You like working collaboratively in an interdisciplinary, fast-paced environment
  • You believe in silico/AI can have strong impact on how to find new drugs
  • You want to join a small team to bring your own impact in drug discovery

To apply, send us your CV: careers@aqemia.com

Aqemia is growing fast. You do not fit in this job description but are excited by this adventure? Contact us!